Piero Parchi Selected Research

Prion Proteins

1/2022	The Use of Real-Time Quaking-Induced Conversion for the Diagnosis of Human Prion Diseases.
1/2022	PMCA-Based Detection of Prions in the Olfactory Mucosa of Patients With Sporadic Creutzfeldt-Jakob Disease.
10/2021	The First Sporadic Creutzfeldt-Jakob Disease Case with a Rare Molecular Subtype VV1 and 1-Octapeptide Repeat Deletion in PRNP.
10/2021	Phenotypic diversity of genetic Creutzfeldt-Jakob disease: a histo-molecular-based classification.
1/2021	Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease.
10/2020	Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study.
1/2020	Towards an improved early diagnosis of neurodegenerative diseases: the emerging role of in vitro conversion assays for protein amyloids.
1/2020	CSF SerpinA1 in Creutzfeldt-Jakob disease and frontotemporal lobar degeneration.
12/2019	Domain-specific Quantification of Prion Protein in Cerebrospinal Fluid by Targeted Mass Spectrometry.
11/2019	Molecular Characterization of the Danish Prion Diseases Cohort With Special Emphasis on Rare and Unique Cases.

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Piero Parchi Research Topics

Disease

44	Prion Diseases (Transmissible Spongiform Encephalopathies) 10/2022 - 03/2003
34	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 01/2022 - 10/2003
21	Dementia (Dementias) 01/2022 - 01/2008
18	Sporadic Creutzfeldt-Jakob Disease 02/2022 - 04/2003
18	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 03/2003
16	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 10/2003
15	Acquired CJD 01/2020 - 01/2003
7	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2021 - 07/2015
7	Sleep Initiation and Maintenance Disorders (Insomnia) 11/2019 - 01/2003
6	Fatal Familial Insomnia 01/2019 - 10/2004
6	Amyloid Plaque 01/2018 - 02/2010
5	Disease Progression 01/2021 - 04/2013
5	Scrapie 01/2018 - 10/2003
5	Kuru 11/2017 - 10/2010
4	Parkinson Disease (Parkinson's Disease) 10/2021 - 01/2008
3	Gliosis 02/2022 - 01/2018
3	Cognitive Dysfunction 01/2022 - 01/2021
3	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 10/2020 - 01/2020
3	Neuroinflammatory Diseases 06/2020 - 12/2019
3	Tauopathies 01/2020 - 01/2018
3	Frontotemporal Dementia (Semantic Dementia) 01/2020 - 01/2018
3	Corticobasal Degeneration 01/2020 - 01/2017
3	Synucleinopathies 01/2020 - 01/2008
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 06/2020
2	Parkinsonian Disorders (Parkinsonism) 10/2021 - 01/2020
2	Lewy Body Disease (Lewy Body Dementia) 01/2021 - 01/2008
2	Narcolepsy 01/2020 - 06/2014
2	Proteostasis Deficiencies 01/2019 - 01/2018
2	Amyloidosis 06/2018 - 02/2010
2	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2018 - 02/2010
2	Myoclonus (Nocturnal Myoclonus) 01/2018 - 10/2009
2	Infections 01/2011 - 01/2010
1	Orthostatic Hypotension (Postural Hypotension) 10/2021
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2021
1	Autoimmune Diseases of the Nervous System 01/2021
1	Pick Disease of the Brain (Pick's Disease) 01/2020
1	Normal Pressure Hydrocephalus 01/2019
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2019
1	Olivary Degeneration 01/2019
1	Neurologic Manifestations (Neurological Manifestations) 01/2018
1	Ataxia (Dyssynergia) 01/2018
1	Rare Diseases (Rare Disease) 11/2017

Drug/Important Bio-Agent (IBA)

49	Prion ProteinsIBA 01/2022 - 04/2003
34	PrionsIBA 01/2022 - 03/2003
23	Biomarkers (Surrogate Marker)IBA 01/2022 - 05/2013
22	Codon (Codons)IBA 10/2021 - 01/2003
21	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2014
13	Methionine (L-Methionine)FDA Link 10/2021 - 09/2006
12	Peptide Hydrolases (Proteases)FDA Link 10/2022 - 01/2003
11	Valine (L-Valine)FDA Link 10/2021 - 09/2006
10	SynucleinsIBA 01/2022 - 01/2008
6	Amyloid (Amyloid Fibrils)IBA 01/2022 - 02/2010
5	diazonaphthalenedisulfonic acid (NDS)IBA 01/2022 - 11/2018
5	Protein Isoforms (Isoforms)IBA 01/2020 - 10/2003
4	Biological ProductsIBA 01/2021 - 01/2011
4	Endopeptidase K (Proteinase K)IBA 01/2018 - 10/2003
3	Amyloid beta-PeptidesIBA 10/2021 - 10/2008
3	14-3-3 Proteins (14-3-3 Protein)IBA 11/2020 - 04/2015
3	AntibodiesIBA 11/2014 - 11/2007
2	Peptides (Polypeptides)IBA 02/2022 - 12/2019
2	Apolipoproteins E (ApoE)IBA 01/2022 - 01/2019
2	ProgranulinsIBA 01/2021 - 01/2017
2	tau Proteins (tau Protein)IBA 10/2020 - 01/2020
2	Amyloidogenic ProteinsIBA 01/2020 - 01/2020
2	Protein AggregatesIBA 12/2019 - 11/2008
2	ImmunosorbentsIBA 12/2019 - 11/2018
2	EnzymesIBA 12/2019 - 11/2018
2	PrPSc ProteinsIBA 11/2014 - 04/2013
1	preproenkephalinIBA 02/2022
1	proenkephalinIBA 02/2022
1	antineoplaston A10 (A 10)IBA 01/2022
1	alpha-SynucleinIBA 10/2021
1	LDL Receptors (LDL Receptor)IBA 01/2021
1	SphingolipidsIBA 10/2020
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020
1	N 30IBA 01/2020
1	UbiquitinIBA 01/2020
1	chitotriosidaseIBA 12/2019
1	Glial Fibrillary Acidic ProteinIBA 12/2019
1	Chitinase-3-Like Protein 1IBA 12/2019
1	Indicators and Reagents (Reagents)IBA 12/2019
1	RNA (Ribonucleic Acid)IBA 07/2019
1	Pharmaceutical PreparationsIBA 01/2019
1	Aspartic Acid (Aspartate)FDA Link 01/2019
1	AsparagineIBA 01/2019
1	ApolipoproteinsIBA 01/2019
1	SerpinsIBA 01/2018
1	Amino Acids FDA Link 01/2018
1	thioflavin TIBA 01/2018
1	Growth Hormone (Somatotropin)IBA 01/2018
1	Presenilin-1IBA 01/2018
1	Adenosine Monophosphate (AMP)IBA 01/2018
1	Protein Kinases (Protein Kinase)IBA 01/2018
1	Presenilin-2IBA 01/2018
1	GranulinsIBA 01/2018
1	CeroidIBA 01/2017
1	LipofuscinIBA 01/2017

Therapy/Procedure

2	Therapeutics 12/2019 - 01/2019
1	Precision Medicine 01/2021
1	Transplantation 01/2019